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Genetic Testing Info
Wyatt and Josey, are both 100% clear for the entire Paw Print Genetics, genetic disease panel and for a form of Cardiomyopathy. Both have been tested for various color and pattern traits as well as the shedding gene. Even color genes can cause health problems..... Please click on a logo to view test results. You'll find Jane's test results here also. Wyatt and Josey were also evaluated by and eye specialist and those results were recorded thru OFA. Click on a dog's name below to see their eye evaluation status with OFA. KCR's Wyatt Earp Yeakey's Josephine Earp |
What is a “Carrier” of a Recessive disease? - Copied from Paw Print Genetics
Recessive inherited diseases are those in which an individual must inherit two copies of a mutated gene (one from each parent) in order to develop the associated condition. Dogs inheriting two copies of the mutation are typically not recommended for breeding because even if bred to a dog that does not have the same genetic mutation, every puppy from the litter would inherit a single copy of the disease-associated mutation, thereby increasing the frequency of the mutation in the breed population to a significant degree.
Dogs inheriting one copy of the mutation from a single parent are considered “carriers” of the disease and will not develop clinical signs of the disease themselves. However, when bred with another dog which carries the same mutation, approximately 25% of the offspring will inherit two copies of the mutation and will be at risk for or affected with the associated condition. Therefore, in general, it is recommended to only breed a carrier to a dog that is clear of the mutation. Using statistics as a guide, this strategy is expected to result in a litter consisting of approximately 50% carrier offspring and 50% normal or “clear” offspring. Thus, avoiding the removal of the carrier dog and its unique combination of genetic variants that contribute to the overall genetic diversity of the breed while limiting the number of puppies born with the known, disease-associated mutation.
Recessive diseases are particularly troubling for breeders because dogs inheriting a single copy of a disease-causing mutation (“carriers”) do not show signs of the disease, but can produce puppies with the disease if bred to another carrier of the same mutation. When it comes to genetic diseases, Ben Franklin had it right when he stated, “An ounce of prevention is worth a pound of cure.” In a perfect world in which every dog breeder performed genetic disease testing on their breeding stock and made selective breeding decisions using these results, diseases caused by over 200 known canine genetic mutations could be completely prevented
To learn more about health conditions and why it is important to buy from breeders who test, follow the link below:
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